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Association of Clonal Hematopoiesis of...
Journal article

Association of Clonal Hematopoiesis of Indeterminate Potential with Cardiovascular Events in Patients with CKD

Abstract

Key Points In patients with CKD, non- DNMT3A clonal hematopoiesis of indeterminate potential (CHIP) was associated with higher risk of cardiovascular events. There was no significant difference in the CHIP–cardiovascular disease association based on baseline eGFR, diabetes status, or race. The protective effect of IL6R p.Asp358Ala on non- DNMT3A CHIP cardiovascular risk was similar to the general population. Background Patients …

Authors

Pan Y; Vlasschaert C; Rao V; Akwo EA; Hixson JE; Uddin M; Yu Z; Kim D-K; Bick A; Kestenbaum B

Journal

Journal of the American Society of Nephrology, Vol. 36, No. 9, pp. 1775–1785

Publisher

Wolters Kluwer

Publication Date

9 2025

DOI

10.1681/asn.0000000671

ISSN

1046-6673

Labels

Sustainable Development Goals (SDG)