Journal article
Upregulation of HSP90α in the lungs and circulation in sarcoidosis
Abstract
Background: Sarcoidosis is a systemic granulomatous disease of unknown cause. Natural improvement with favorable outcome is common, but a significant number of patients present with difficult to manage and progressive disease. The identification of biomarkers associated with disease activity and progression is warranted. Extracellular heat shock protein 90 (HSP90) α is a signaling molecule released by cells that induces proinflammatory …
Authors
Isshiki T; Sunakawa M; Vierhout M; Ayoub A; Ali P; Naiel S; Miyoshi S; Naqvi A; Hambly N; Kishi K
Journal
Frontiers in Medicine, Vol. 12, ,
Publisher
Frontiers
DOI
10.3389/fmed.2025.1532437
ISSN
2296-858X