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Diversity, functional classification and...
Journal article

Diversity, functional classification and genotyping of SHV β-lactamases in Klebsiella pneumoniae

Abstract

Interpreting the phenotypes of bla SHV alleles in Klebsiella pneumoniae genomes is complex. Whilst all strains are expected to carry a chromosomal copy conferring resistance to ampicillin, they may also carry mutations in chromosomal bla SHV alleles or additional plasmid-borne bla SHV alleles that have extended-spectrum β-lactamase (ESBL) activity and/or β-lactamase inhibitor (BLI) resistance activity. In addition, the role of individual …

Authors

Tsang KK; Lam MMC; Wick RR; Wyres KL; Bachman M; Baker S; Barry K; Brisse S; Campino S; Chiaverini A

Journal

Microbial Genomics, Vol. 10, No. 10,

Publisher

Microbiology Society

Publication Date

October 21, 2024

DOI

10.1099/mgen.0.001294

ISSN

2057-5858