Journal article
Monocyte-driven inflamm-aging reduces intestinal barrier function in females
Abstract
BackgroundThe intestinal barrier encompasses physical and immunological components that act to compartmentalize luminal contents, such as bacteria and endotoxins, from the host. It has been proposed that an age-related decline of intestinal barrier function may allow for the passage of luminal contents into the bloodstream, triggering a low-grade systemic inflammation termed inflamm-aging. Although there is mounting evidence to support this …
Authors
Quin C; Breznik JA; Kennedy AE; DeJong EN; Andary CM; Ermolina S; Davidson DJ; Ma J; Surette MG; Bowdish DME
Journal
Immunity & Ageing, Vol. 21, No. 1,
Publisher
Springer Nature
DOI
10.1186/s12979-024-00469-6
ISSN
1742-4933