Journal article
Methyl-CCNU and Methotrexate Therapy in Patients with Advanced Colorectal Cancer After Failure of 5-Fluorouracil Chemotherapy
Abstract
Thirty-six patients with advanced colorectal cancer whose disease progressed during treatment with 5-fluorouracil (5-FU) chemotherapy were treated with methyl-CCNU and methotrexate. Five patients (14%) achieved a partial response (PR), three (8%) showed disease regression less than that required for a PR, and three (8%) showed evidence of stable disease. Twenty-five patients (69%) progressed on treatment. Tumor regression was seen only in …
Authors
Zorzitto ML; Myers R; Bazos MJ; Shepherd FA; Evans WK
Journal
American Journal of Clinical Oncology, Vol. 9, No. 1, pp. 27–30
Publisher
Wolters Kluwer
Publication Date
February 1986
DOI
10.1097/00000421-198602000-00008
ISSN
0277-3732