External validation and comparison of six cardiovascular risk prediction models in the Prospective Urban Rural Epidemiology (PURE)-Colombia study

AIMS: To externally validate the SCORE2, AHA/ACC pooled cohort equation (PCE), Framingham Risk Score (FRS), Non-Laboratory INTERHEART Risk Score (NL-IHRS), Globorisk-LAC, and WHO prediction models and compare their discrimination and calibration capacity. METHODS AND RESULTS: Validation in individuals aged 40-69 years with at least 10 years of follow-up and without baseline use of statins or cardiovascular diseases from the Prospective Urban …