Journal article
MDSCs, ageing and inflammageing
Abstract
The challenge of distinguishing between changes attributable to ageing and those attributable to pathology is even greater for the immune system than for many other organs, and this is especially true for myeloid-derived suppressor cells (MDSCs). Hematopoiesis is different in older adults with a bias towards myelopoiesis, and older adults also manifest "inflammageing" exacerbated by disease and contributing to MDSC induction. Hence, at least in …
Authors
Pawelec G; Picard E; Bueno V; Verschoor CP; Ostrand-Rosenberg S
Journal
Cellular Immunology, Vol. 362, ,
Publisher
Elsevier
Publication Date
April 2021
DOI
10.1016/j.cellimm.2021.104297
ISSN
0008-8749