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Intraretinal Hyper-Reflective Foci Are Almost...
Journal article

Intraretinal Hyper-Reflective Foci Are Almost Universally Present and Co-Localize With Intraretinal Fluid in Diabetic Macular Edema

Abstract

Purpose: In diabetic macular edema (DME), hyper-reflective foci (HRF) has been linked to disease severity and progression. Using an automated approach, we aimed to investigate the baseline distribution of HRF in DME and their co-localization with cystoid intraretinal fluid (IRF). Methods: Baseline spectral-domain optical coherence tomography (SD-OCT) volume scans (N = 1527) from phase III clinical trials YOSEMITE (NCT03622580) and RHINE …

Authors

von Schulthess EL; Maunz A; Chakravarthy U; Holekamp N; Pauleikhoff D; Patel K; Bachmeier I; Yu S; Cohen Y; Scherb MP

Journal

Investigative Ophthalmology & Visual Science, Vol. 65, No. 5,

Publisher

Association for Research in Vision and Ophthalmology (ARVO)

Publication Date

May 17, 2024

DOI

10.1167/iovs.65.5.26

ISSN

0146-0404