Journal article
A Significant Contribution of the Classical Pathway of Complement in SARS-CoV-2 Neutralization of Convalescent and Vaccinee Sera.
Abstract
Although high titers of neutralizing Abs in human serum are associated with protection from reinfection by SARS-CoV-2, there is considerable heterogeneity in human serum-neutralizing Abs against SARS-CoV-2 during convalescence between individuals. Standard human serum live virus neutralization assays require inactivation of serum/plasma prior to testing. In this study, we report that the SARS-CoV-2 neutralization titers of human convalescent …
Authors
Budylowski P; Chau SLL; Banerjee A; Guvenc F; Samson R; Hu Q; Fiddes L; Seifried L; Chao G; Buchholz M
Journal
The Journal of Immunology, Vol. 212, No. 12, pp. 1922–1931
Publisher
Oxford University Press (OUP)
Publication Date
June 15, 2024
DOI
10.4049/jimmunol.2300320
ISSN
0022-1767