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Respiratory drive heterogeneity associated with...
Journal article

Respiratory drive heterogeneity associated with systemic inflammation and vascular permeability in acute respiratory distress syndrome

Abstract

BackgroundIn acute respiratory distress syndrome (ARDS), respiratory drive often differs among patients with similar clinical characteristics. Readily observable factors like acid–base state, oxygenation, mechanics, and sedation depth do not fully explain drive heterogeneity. This study evaluated the relationship of systemic inflammation and vascular permeability markers with respiratory drive and clinical outcomes in ARDS.MethodsARDS patients …

Authors

Baedorf-Kassis E; Murn M; Dzierba AL; Serra AL; Garcia I; Minus E; Padilla C; Sarge T; Goodspeed VM; Matthay MA

Journal

Critical Care, Vol. 28, No. 1,

Publisher

Springer Nature

DOI

10.1186/s13054-024-04920-4

ISSN

1364-8535