Journal article
Characterization of a rat model of metastatic prostate cancer bone pain
Abstract
PURPOSE: The objectives of this study were to establish and characterize a novel animal model of metastatic prostate cancer-induced bone pain.
METHODS: Copenhagen rats were injected with 10(6) MATLyLu (MLL) prostate cancer cells or phosphate-buffered saline by per cutaneous intra femoral injections into the right hind leg distal epiphysis. Over 13 days, rats progressively developed a tumor within the distal femoral epiphysis. On days 3, 7, 10, …
Authors
De Ciantis PD; Yashpal K; Henry J; Singh G
Journal
Journal of Pain Research, Vol. 3, No. 0, pp. 213–221
Publisher
Taylor & Francis
Publication Date
November 8, 2010
DOI
10.2147/jpr.s14209
ISSN
1178-7090