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The organization of melatonin in lipid membranes
Journal article

The organization of melatonin in lipid membranes

Abstract

Melatonin is a hormone that has been shown to have protective effects in several diseases that are associated with cholesterol dysregulation, including cardiovascular disease, Alzheimer's disease, and certain types of cancers. We studied the interaction of melatonin with model membranes made of dimyristoylphosphatidylcholine (DMPC) at melatonin concentrations ranging from 0.5mol% to 30mol%. From 2-dimensional X-ray diffraction measurements, we …

Authors

Dies H; Cheung B; Tang J; Rheinstädter MC

Journal

Biochimica et Biophysica Acta, Vol. 1848, No. 4, pp. 1032–1040

Publisher

Elsevier

Publication Date

April 2015

DOI

10.1016/j.bbamem.2015.01.006

ISSN

0006-3002