A systematic review of abnormalities in intracortical myelin across psychiatric illnesses

Background Brain imaging studies have thoroughly investigated brain gray matter abnormalities to assess pathophysiological mechanisms underlying psychiatric illnesses, however white matter has only recently been investigated. Abnormalities in myelination and white matter structures found in the cerebral cortex, known as intracortical myelin (ICM), have been linked with psychiatric illnesses including bipolar disorder (BD) and schizophrenia …