In AF, the effects of DOACs vs. warfarin on death and stroke/systemic embolism vary by baseline CrCl level
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Harrington J, Carnicelli AP, Hua K, et al. Direct oral anticoagulants versus warfarin across the spectrum of kidney function: patient-level network meta-analyses from COMBINE AF. Circulation. 2023;147:1748-1757. 37042255.