Journal article
Phylogenomic Analysis of 155 Helminth Species Reveals Widespread Absence of Oxygen Metabolic Capacity
Abstract
The terminal electron acceptor of most aerobic respiratory chains, cytochrome c oxidase (COX), has been highly conserved throughout evolution, from aerobic prokaryotes to complex eukaryotes. Oxygen metabolism in parasitic helminths differs significantly from that of most aerobic eukaryotes, as these organisms can switch between aerobic and anaerobic metabolisms throughout their life cycles. Early studies suggested a lack of COX activity in …
Authors
Collington E; Lobb B; Abu Mazen N; Doxey AC; Glerum DM
Journal
Genome Biology and Evolution, Vol. 15, No. 8,
Publisher
Oxford University Press (OUP)
Publication Date
August 1, 2023
DOI
10.1093/gbe/evad135
ISSN
1759-6653