Journal article
Association of Genetic Variant Linked to Hemochromatosis With Brain Magnetic Resonance Imaging Measures of Iron and Movement Disorders
Abstract
Importance: Hereditary hemochromatosis (HH) is an autosomal recessive genetic disorder that leads to iron overload. Conflicting results from previous research has led some to believe the brain is spared the toxic effects of iron in HH.
Objective: To test the association of the strongest genetic risk variant for HH on brainwide measures sensitive to iron deposition and the rates of movement disorders in a substantially larger sample than …
Authors
Loughnan R; Ahern J; Tompkins C; Palmer CE; Iversen J; Thompson WK; Andreassen O; Jernigan T; Sugrue L; Dale A
Journal
JAMA Neurology, Vol. 79, No. 9, pp. 919–928
Publisher
American Medical Association (AMA)
Publication Date
September 1, 2022
DOI
10.1001/jamaneurol.2022.2030
ISSN
2168-6149