Journal article
Mettl14 mutation restrains liver regeneration by attenuating mitogens derived from non-parenchymal liver cells
Abstract
Liver regeneration is a well-known systemic homeostatic phenomenon. The N6-methyladenosine (m6A) modification pathway has been associated with liver regeneration and hepatocellular carcinoma. m6A methyltransferases, such as methyltransferase 3 (METTL3) and methyltransferase 14 (METTL14), are involved in the hepatocyte-specific-regenerative pathway. To illustrate the role of METTL14, secreted from non-parenchymal liver cells, in the initiation …
Authors
Yang I; Oh SY; Jang S; Kim IY; Sung YM; Seong JK
Journal
BMB Reports, Vol. 55, No. 12, pp. 633–638
Publisher
Korean Society for Biochemistry and Molecular Biology - BMB Reports
Publication Date
December 31, 2022
DOI
10.5483/bmbrep.2022.55.12.140
ISSN
1976-6696