Handgrip exercise increases platelet‐bound BDNF in an intensity‐dependent manner

Introduction Brain‐derived neurotrophic factor (BDNF) is a major orchestrator of exercise‐induced brain plasticity, and evidence suggests that peripheral BDNF has central effects. Consequently, exploration into the mechanisms that increase peripheral BDNF has important implications for improving brain health through exercise. The majority of blood‐borne BDNF is bound to platelets, which sequester, store, and release the neurotrophin under …