Journal article
The association of sensitivity and specificity with disease prevalence: analysis of 6909 studies of diagnostic test accuracy
Abstract
BACKGROUND: Sensitivity and specificity are characteristics of a diagnostic test and are not expected to change as the prevalence of the target condition changes. We sought to evaluate the association between prevalence and changes in sensitivity and specificity.
METHODS: We retrieved data from meta-analyses of diagnostic test accuracy published in the Cochrane Database of Systematic Reviews (2003-2020). We used mixed-effects random-intercept …
Authors
Murad MH; Lin L; Chu H; Hasan B; Alsibai RA; Abbas AS; Mustafa RA; Wang Z
Journal
Canadian Medical Association Journal, Vol. 195, No. 27, pp. e925–e931
Publisher
Joule
Publication Date
July 17, 2023
DOI
10.1503/cmaj.221802
ISSN
0820-3946