Journal article
On the role of abnormal DLCO in ex-smokers without airflow limitation: symptoms, exercise capacity and hyperpolarised helium-3 MRI
Abstract
BACKGROUND: The functional effects of abnormal diffusing capacity for carbon monoxide (DLCO) in ex-smokers without chronic obstructive pulmonary disease (COPD) are not well understood.
OBJECTIVE: We aimed to evaluate and compare well established clinical, physiological and emerging imaging measurements in ex-smokers with normal spirometry and abnormal DLCO with a group of ex-smokers with normal spirometry and DLCO and ex-smokers with Global …
Authors
Kirby M; Owrangi A; Svenningsen S; Wheatley A; Coxson HO; Paterson NAM; McCormack DG; Parraga G
Journal
Thorax, Vol. 68, No. 8,
Publisher
BMJ
Publication Date
August 2013
DOI
10.1136/thoraxjnl-2012-203108
ISSN
0040-6376
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AgedAged, 80 and overAntimetabolitesCarbon MonoxideDiffusion Magnetic Resonance ImagingExercise ToleranceFemaleFollow-Up StudiesForced Expiratory VolumeHeliumHumansMaleMiddle AgedPlethysmographyPulmonary Disease, Chronic ObstructiveRespiratory Function TestsSmokingSurveys and QuestionnairesTomography, X-Ray ComputedVital Capacity