Journal article
Pulmonary ventilation defects in older never-smokers
Abstract
Hyperpolarized (3)He MRI previously revealed spatially persistent ventilation defects in healthy, older compared with healthy, younger never-smokers. To understand better the physiological consequences and potential relevance of (3)He MRI ventilation defects, we evaluated (3)He-MRI ventilation-defect percent (VDP) and the effect of deep inspiration (DI) and salbutamol on VDP in older never-smokers. To identify the potential determinants of …
Authors
Sheikh K; Paulin GA; Svenningsen S; Kirby M; Paterson NAM; McCormack DG; Parraga G
Journal
Journal of Applied Physiology, Vol. 117, No. 3, pp. 297–306
Publisher
American Physiological Society
Publication Date
August 1, 2014
DOI
10.1152/japplphysiol.00046.2014
ISSN
8750-7587