Journal article
Fixed dose combination therapies in primary cardiovascular disease prevention in different groups: an individual participant meta-analysis
Abstract
OBJECTIVE: To evaluate the effects of fixed dose combination (FDC) medications on cardiovascular outcomes in different age groups in an individual participant meta-analysis of three primary prevention randomised trials.
METHODS: Participants at intermediate risk (17.7% mean 10-year Framingham Cardiovascular Risk Score), randomised to FDC of two or more antihypertensives and a statin with or without aspirin, or to their respective control, were …
Authors
Dagenais GR; Pais P; Gao P; Roshandel G; Malekzadeh R; Joseph P; Yusuf S
Journal
Heart, Vol. 109, No. 18, pp. 1372–1379
Publisher
BMJ
Publication Date
9 2023
DOI
10.1136/heartjnl-2022-322278
ISSN
1355-6037