Journal article
Evaluation of the Suitability of RNAscope as a Technique to Measure Gene Expression in Clinical Diagnostics: A Systematic Review
Abstract
ObjectiveTo evaluate the application of RNAscope in the clinical diagnostic field compared to the current ‘gold standard’ methods employed for testing gene expression levels, including immunohistochemistry (IHC), quantitative real time PCR (qPCR), and quantitative reverse transcriptase PCR (qRT-PCR), and to detect genes, including DNA in situ hybridisation (DNA ISH).MethodsThis systematic review searched CINAHL, Medline, Embase and Web of …
Authors
Atout S; Shurrab S; Loveridge C
Journal
Molecular Diagnosis & Therapy, Vol. 26, No. 1, pp. 19–37
Publisher
Springer Nature
Publication Date
January 2022
DOI
10.1007/s40291-021-00570-2
ISSN
1177-1062