Chapter
CHAPTER 8
Abstract
DNA, long known as a carrier of genetic information, has recently revealed itself as a multifunctional entity. Using the powerful technique of in vitro selection, catalytic DNA molecules, known as DNAzymes or deoxyribozymes, have been isolated to catalyse numerous reactions using a range of metal-ion cofactors. Conjugation of these DNAzymes to an array of signalling platforms has led to the development of several DNAzyme-based sensor systems. …
Authors
McManus SA; Tram K; Li* Y
Book title
DNA Conjugates and Sensors
Pagination
pp. 190-210
Publisher
Royal Society of Chemistry (RSC)
Publication Date
October 18, 2012
DOI
10.1039/9781849734936-00190