Journal article
Impaired ability of burn patient neutrophils to stimulate β‐defensin production by keratinocytes
Abstract
Immunosuppressive neutrophils (PMN-II) appearing in association with burn injury have a role on the increased susceptibility of burn patients to various infections. In the present study, the role of PMN-II on the production of human β-defensins (HBDs), important molecules on host antimicrobial innate immunities, by human keratinocytes was studied. Normal human epidermal keratinocytes (NHEKs) were cultured with neutrophils (PMNs) isolated from …
Authors
Kawasaki T; Nakamura K; Jeschke MG; Kogiso M; Kobayashi M; Herndon DN; Suzuki F
Journal
Immunology and Cell Biology, Vol. 90, No. 8, pp. 796–801
Publisher
Wiley
Publication Date
September 2012
DOI
10.1038/icb.2012.3
ISSN
0818-9641