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Early sex-dependent differences in metabolic...
Journal article

Early sex-dependent differences in metabolic profiles of overweight and adiposity in young children: a cross-sectional analysis

Abstract

BackgroundChildhood obesity is a global health concern and can lead to lifetime cardiometabolic disease. New advances in metabolomics can provide biochemical insights into the early development of obesity, so we aimed to characterize serum metabolites associated with overweight and adiposity in early childhood and to stratify associations by sex.MethodsNontargeted metabolite profiling was conducted in the Canadian CHILD birth cohort (discovery …

Authors

Azab SM; Shanmuganathan M; de Souza RJ; Kroezen Z; Desai D; Williams NC; Morrison KM; Atkinson SA; Teo KK; Azad MB

Journal

BMC Medicine, Vol. 21, No. 1,

Publisher

Springer Nature

DOI

10.1186/s12916-023-02886-8

ISSN

1741-7015