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Efficacy and Safety of Anti-Xa-Guided Versus Fixed...
Journal article

Efficacy and Safety of Anti-Xa-Guided Versus Fixed Dosing of Low Molecular Weight Heparin for Prevention of Venous Thromboembolism in Trauma Patients

Abstract

PURPOSE: Trauma patients are at high risk of venous thromboembolism (VTE). We summarize the comparative efficacy and safety of anti-Xa-guided versus fixed dosing for low molecular weight heparin (LMWH) for the prevention of VTE in adult trauma patients. METHODS: We searched Medline and Embase from inception through June 1, 2022. We included randomized controlled trials or observational studies comparing anti-Xa-guided versus fixed dosing of …

Authors

Tran A; Fernando SM; Gates RS; Gillen JR; Droege ME; Carrier M; Inaba K; Haut ER; Cotton B; Teichman A

Journal

Annals of Surgery, Vol. 277, No. 5, pp. 734–741

Publisher

Wolters Kluwer

Publication Date

May 2023

DOI

10.1097/sla.0000000000005754

ISSN

0003-4932