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Effect of low dose denosumab on bone mineral...
Journal article

Effect of low dose denosumab on bone mineral density in postmenopausal women with osteoporosis after a transition from 60 mg dose: a prospective observational study

Abstract

IntroductionDenosumab is an effective antiresorptive molecule and reduces the risk of fracture in postmenopausal osteoporosis. Cessation of denosumab therapy however is associated with rapid declines in bone mineral density (BMD), rises in bone remodeling, and an increased risk of fracture. We evaluated the effect of low dose denosumab (30 mg every 6 months) on the prevention of bone loss following a switch from standard dose (60 mg of …

Authors

Khan AA; AbuAlrob H; M’Hiri I; Ali DS; Dandurand K; Said H; Alkassem H; Hakami Y; Hweija I; Iqbal S

Journal

Endocrine, Vol. 80, No. 3, pp. 647–657

Publisher

Springer Nature

Publication Date

June 2023

DOI

10.1007/s12020-022-03230-5

ISSN

1355-008X