Journal article
Peroxisomal membrane monocarboxylate transporters: evidence for a redox shuttle system?
Abstract
One of the many functions of liver peroxisomes is the beta-oxidation of long-chain fatty acids. It is essential for the continuation of peroxisomal beta-oxidation that a redox shuttle system exist across the peroxisomal membrane to reoxidize NADH. We propose that this redox shuttle system consists of a substrate cycle between lactate and pyruvate. Here we present evidence that purified peroxisomal membranes contain both monocarboxylate …
Authors
McClelland GB; Khanna S; González GF; Butz CE; Brooks GA
Journal
Biochemical and Biophysical Research Communications, Vol. 304, No. 1, pp. 130–135
Publisher
Elsevier
Publication Date
4 2003
DOI
10.1016/s0006-291x(03)00550-3
ISSN
0006-291X