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Loss of age-related laminar differentiation of...
Journal article

Loss of age-related laminar differentiation of intracortical myelin in bipolar disorder

Abstract

Age-related changes of intracortical myelin in bipolar disorder (BD) have been observed to deviate from the quadratic age curve observed in healthy controls (HC), but it is unclear if this holds at varying cortical depths. From BD (n = 44; age range = 17.6-45.5 years) and HC (n = 60; age range = 17.1-45.8 years) participants, we collected 3T T1-weighted (T1w) images with strong intracortical contrast. Signal values were sampled from 3 …

Authors

Suh JS; Rowley CD; Sehmbi M; Tardif CL; Minuzzi L; Bock NA; Frey BN

Journal

Cerebral Cortex, Vol. 33, No. 12, pp. 7468–7476

Publisher

Oxford University Press (OUP)

Publication Date

June 8, 2023

DOI

10.1093/cercor/bhad052

ISSN

1047-3211