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Effects of a Polypill, Aspirin, and the...
Journal article

Effects of a Polypill, Aspirin, and the Combination of Both on Cognitive and Functional Outcomes

Abstract

Importance: Vascular risk factors are associated with cognitive decline but studies addressing individual risk factors have not demonstrated an effect of risk factor management on the preservation of cognition. Few trials have examined the effect of vascular risk factor management on function. Objective: To determine if a polypill could reduce cognitive and functional decline in people with risk factors but without manifest cardiovascular …

Authors

Bosch JJ; O'Donnell MJ; Gao P; Joseph P; Pais P; Xavier D; Dans A; Lopez Jaramillo P; Yusuf S

Journal

JAMA Neurology, Vol. 80, No. 3, pp. 251–259

Publisher

American Medical Association (AMA)

Publication Date

March 1, 2023

DOI

10.1001/jamaneurol.2022.5088

ISSN

2168-6149