Journal article
Rationale and design of the colchicine for the prevention of perioperative atrial fibrillation in patients undergoing major noncardiac thoracic surgery (COP-AF) trial
Abstract
BACKGROUND: Perioperative atrial fibrillation (AF) and myocardial injury after noncardiac surgery (MINS) are common complications after noncardiac surgery. Inflammation has been implicated in the pathogenesis of both disorders. The COP-AF trial tests the hypothesis that colchicine reduces the incidence of perioperative AF and MINS in patients undergoing major noncardiac thoracic surgery.
METHODS AND RESULTS: The 'COlchicine for the Prevention …
Authors
Conen D; Popova E; Wang MK; Chan MTV; Landoni G; Reimer C; Srinathan SK; Cata JP; McLean SR; Trujillo Reyes JC
Journal
American Heart Journal, Vol. 259, , pp. 87–96
Publisher
Elsevier
Publication Date
May 2023
DOI
10.1016/j.ahj.2023.01.018
ISSN
0002-8703