Journal article
The Observation of Highly Ordered Domains in Membranes with Cholesterol
Abstract
Rafts, or functional domains, are transient nano- or mesoscopic structures in the exoplasmic leaflet of the plasma membrane, and are thought to be essential for many cellular processes. Using neutron diffraction and computer modelling, we present evidence for the existence of highly ordered lipid domains in the cholesterol-rich (32.5 mol%) liquid-ordered ([Formula: see text]) phase of dipalmitoylphosphatidylcholine membranes. The liquid ordered …
Authors
Armstrong CL; Marquardt D; Dies H; Kučerka N; Yamani Z; Harroun TA; Katsaras J; Shi A-C; Rheinstädter MC
Journal
PLOS ONE, Vol. 8, No. 6,
Publisher
Public Library of Science (PLoS)
Publication Date
2013
DOI
10.1371/journal.pone.0066162
ISSN
1932-6203