The role of kallikreins in growth factor processing: the kallikrein gene family from the African rodent Mastomys.

1. Kallikreins are trypsin-like serine proteases which have been implicated in the biosynthesis of a number of growth factors and hormones. Mastomys, an African rodent, is the only mammal other than mouse known to contain high levels of kallikreins and growth factors in its submandibular gland. Mastomys has a large kallikrein family similar to mouse and rat. Cloning and sequencing of several of these cDNAs demonstrates a high degree of homology …