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Kaiso depletion attenuates transforming growth...
Journal article

Kaiso depletion attenuates transforming growth factor-β signaling and metastatic activity of triple-negative breast cancer cells

Abstract

Triple-negative breast cancers (TNBCs) represent a subset of breast tumors that are highly aggressive and metastatic, and are responsible for a disproportionate number of breast cancer-related deaths. Several studies have postulated a role for the epithelial-to-mesenchymal transition (EMT) program in the increased aggressiveness and metastatic propensity of TNBCs. Although EMT is essential for early vertebrate development and wound healing, it …

Authors

Bassey-Archibong BI; Kwiecien JM; Milosavljevic SB; Hallett RM; Rayner LGA; Erb MJ; Crawford-Brown CJ; Stephenson KB; Bédard P-A; Hassell JA

Journal

Oncogenesis, Vol. 5, No. 3, pp. e208–e208

Publisher

Springer Nature

Publication Date

3 2016

DOI

10.1038/oncsis.2016.17

ISSN

2157-9024