Journal article
Comparison of the In Vivo Photodynamic Threshold Dose for Photofrin, Mono‐ and Tetrasulfonated Aluminum Phthalocyanine Using a Rat Liver Model
Abstract
The photodynamic threshold dose in normal rat liver was determined from the measured depth of necrosis following surface irradiation. The threshold was determined for the photosensitizing drugs Photofrin and monosulfonated aluminum chlorophthalocyanine, AlPcS1, at 24 h postinjection and was found to be (3.4 x/divided by 1.3) x 10(18) and (8.2 x/divided by 1.5) x 10(18) photons cm-3, respectively, compared with the previously reported value of …
Authors
Farrell TJ; Wilson BC; Patterson MS; Olivo MC
Journal
Photochemistry and Photobiology, Vol. 68, No. 3, pp. 394–399
Publisher
Wiley
Publication Date
September 1998
DOI
10.1111/j.1751-1097.1998.tb09698.x
ISSN
0031-8655