Journal article
Relationship Between mTHPC Fluorescence Photobleaching and Cell Viability During In Vitro Photodynamic Treatment of DP16 Cells
Abstract
An implicit dosimetric model has been proposed in which biological damage caused by photodynamic therapy (PDT) is monitored through the decrease in sensitizer fluorescence during treatment. To investigate this, in vitro experiments were performed in which DP16 cells were incubated in meta-tetra(hydroxyphenyl)chlorin (mTHPC) and then irradiated with 514 nm light. Photosensitizer concentration, fluence rate and oxygenation were independently …
Authors
Dysart JS; Patterson MS; Farrell TJ; Singh G
Journal
Photochemistry and Photobiology, Vol. 75, No. 3, pp. 289–295
Publisher
Wiley
Publication Date
2002
DOI
10.1562/0031-8655(2002)075<0289:rbmfpa>2.0.co;2
ISSN
0031-8655