Journal article
Effect of liposomal confinement on photothermal and photo-oximetric fluorescence lifetimes of photosensitizers with varying hydrophilicity
Abstract
The time-resolved fluorescence of photosensitizers (PSs) of varying hydrophobicities, di-and tetrasulfonated Al phthalocyanines (Al-2 and Al-4), and Photochlor (HPPH), was investigated in liposomes used as cell-mimetic models. Using frequency-and time-domain apparatus, the fluorescence lifetime, tau(fluo), was compared for PSs free in aqueous solution and in a liposome-associated state at varied temperatures (25 to 78 degrees C) and oxygen …
Authors
Mermut O; Noiseux I; Bouchard J-P; Cormier J-F; Desroches P; Fortin M; Gallant P; Leclair S; Vernon ML; Diamond KR
Journal
Journal of Biomedical Optics, Vol. 13, No. 4,
Publisher
SPIE, the international society for optics and photonics
Publication Date
2008
DOI
10.1117/1.2952298
ISSN
1083-3668