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Sexual behavior decreases pain sensitivity and...
Journal article

Sexual behavior decreases pain sensitivity and stimulates endogenous opioids in male rats

Abstract

In male rats copulation has antinociceptive effects as measured either by shock-induced vocalizations or hindlimb withdrawal to pinch. Prolonged mating reduces the content of endogenous opioids in midbrain but not in hypothalamus or caudate nucleus. Blockage of opiate receptors with the narcotic antagonist naloxone (4 mg/kg) significantly extends the postejaculatory interval. The results indicate that mating is a biological stimulus for the …

Authors

Szechtman H; Hershkowitz M; Simantov R

Journal

European Journal of Pharmacology, Vol. 70, No. 3, pp. 279–285

Publisher

Elsevier

Publication Date

3 1981

DOI

10.1016/0014-2999(81)90161-8

ISSN

0014-2999