Journal article
LUSTRE: A Phase III Randomized Trial of Stereotactic Body Radiotherapy (SBRT) vs. Conventionally Hypofractionated Radiotherapy (CRT) for Medically Inoperable Stage I Non-Small Cell Lung Cancer (NSCLC)
Abstract
Purpose/Objective(s) SBRThas been adopted as standard of care for Stage I medically inoperable NSCLC, yet there is inconclusive data from randomized controlled trials (RCT) regarding efficacy. There remains concern regarding long term disease control and toxicity, particularly in centrally located tumors. The purpose of this trial was to compare SBRT to hypofractionated CRT in central and peripheral NSCLC. Materials/Methods A phase III RCT was …
Authors
Swaminath A; Parpia S; Wierzbicki M; Kundapur V; Faria SL; Okawara G; Tsakiridis T; Ahmed N; Bujold A; Hirmiz KJ
Journal
International Journal of Radiation Oncology • Biology • Physics, Vol. 114, No. 5, pp. 1061–1062
Publisher
Elsevier
Publication Date
12 2022
DOI
10.1016/j.ijrobp.2022.09.009
ISSN
0360-3016