Journal article
The kinetics of elimination of salicylic acid and the formation of gentisic acid
Abstract
1. A method for the estimation of gentisic acid in urine has been devised which is based on thin-layer chromatography and fluorimetry.2. In man the urinary excretion of gentisic acid accounted for 0.6% of a 0.32 g dose of aspirin and 1.1% of a 1.28 g dose. The increase in the percentage of the dose excreted as gentisic acid provides further evidence that the elimination of salicylic acid cannot be entirely described by first order kinetics.3. …
Authors
BOREHAM DR; MARTIN BK
Journal
British Journal of Pharmacology, Vol. 37, No. 1, pp. 294–300
Publisher
Wiley
Publication Date
September 1969
DOI
10.1111/j.1476-5381.1969.tb09546.x
ISSN
0007-1188