Journal article
Mapping of the metalloproteinase gene matrilysin (MMP7) to human chromosome 11q21→q22
Abstract
The matrix metalloproteinase, matrilysin, is thought to play an important role in the early steps of tumor progression. We determined the chromosome location of the matrilysin gene (MMP7) by Southern and PCR analysis of two different panels of somatic cell hybrids and in situ hybridization of metaphase chromosomes. Matrilysin maps to the region, 11q21-->q22, adding MMP7 to the cluster of matrix metalloproteinase genes that have already mapped …
Authors
Knox JD; Boreham DR; Walker J-A; Morrison DP; Matrisian LM; Nagle RB; Bowden GT
Journal
Cytogenetic and Genome Research, Vol. 72, No. 2-3, pp. 179–182
Publisher
Karger Publishers
Publication Date
1996
DOI
10.1159/000134181
ISSN
1424-8581