Journal article
125I-Labelled 2-Iodoestrone-3-sulfate: synthesis, characterization and OATP mediated transport studies in hormone dependent and independent breast cancer cells
Abstract
INTRODUCTION: Organic Anion Transporting Polypeptides (OATP) are a family of membrane associated transporters that facilitate estrone-3-sulphate (E3S) uptake by hormone dependent, post-menopausal breast cancers. We have established E3S as a potential ligand for targeting hormone dependent breast cancer cells, and in this study sought to prepare and investigate radioiodinated E3S as a tool to study the OATP system.
METHODS: 2- and …
Authors
Banerjee N; Wu TR; Chio J; Kelly R; Stephenson KA; Forbes J; Allen C; Valliant JF; Bendayan R
Journal
Nuclear Medicine and Biology, Vol. 42, No. 3, pp. 274–282
Publisher
Elsevier
Publication Date
3 2015
DOI
10.1016/j.nucmedbio.2014.10.011
ISSN
0969-8051