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Comparison of Investigator-Reported vs Centrally...
Journal article

Comparison of Investigator-Reported vs Centrally Adjudicated Major Adverse Cardiac Events

Abstract

Importance: In the Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS) trial, there was a significant reduction in the adjudicated primary outcome among patients with stable atherosclerotic vascular disease randomized to dual pathway inhibition (rivaroxaban 2.5 mg twice daily plus aspirin 100 mg daily) vs aspirin monotherapy, but not with rivaroxaban 5 mg twice daily vs aspirin monotherapy. Whether the results are …

Authors

Gaba P; Bhatt DL; Dagenais GR; Bosch J; Maggioni AP; Widimsky P; Leong D; Fox KAA; Yusuf S; Eikelboom JW

Journal

JAMA Network Open, Vol. 5, No. 11,

Publisher

American Medical Association (AMA)

Publication Date

November 1, 2022

DOI

10.1001/jamanetworkopen.2022.43201

ISSN

2574-3805