PITHIA: Protein Interaction Site Prediction Using Multiple Sequence Alignments and Attention

Cellular functions are governed by proteins, and, while some proteins work independently, most work by interacting with other proteins. As a result it is crucially important to know the interaction sites that facilitate the interactions between the proteins. Since the experimental methods are costly and time consuming, it is essential to develop effective computational methods. We present PITHIA, a sequence-based deep learning model for protein …