Journal article
Function and immunogenicity of human parainfluenza virus 3 glycoproteins expressed by recombinant adenoviruses
Abstract
Human parainfluenza virus type 3 fusion (F) and hemagglutinin-neuraminidase (HN) cDNA sequences were inserted into the E3 region of the adenovirus type 5 genome. Cells infected with recombinant adenoviruses containing HPIV3 F (AdF) and HN (AdHN) sequences were shown to express HPIV3 F and HN proteins that were functional and immunogenic. The HN protein produced following AdHN infection was glycosylated, expressed on the surface of infected …
Authors
Ebata SN; Prevec L; Graham FL; Dimock K
Journal
Virus Research, Vol. 24, No. 1, pp. 21–33
Publisher
Elsevier
Publication Date
6 1992
DOI
10.1016/0168-1702(92)90028-8
ISSN
0168-1702