Journal article
Autologous lymphocyte responses to adenovirus-B7-1-transduced human cancer cells
Abstract
Transfection of the costimulatory molecule B7-1 (CD80) into murine tumors can increase antitumor immunity and eradicate tumor growth. The purpose of this study was to test autologous lymphocyte responses against freshly resected human cancers infected in vitro with an adenovirus vector expressing the B7-1 molecule (AdB7). Resected tumors (sarcomas, adenocarcinomas, melanomas, and multiple myelomas) were disaggregated into single-cell …
Authors
Dessureault S; Graham FL; Gallinger S
Journal
Cancer Gene Therapy, Vol. 6, No. 3, pp. 195–208
Publisher
Springer Nature
Publication Date
May 1, 1999
DOI
10.1038/sj.cgt.7700018
ISSN
0929-1903