Conference
Abstract # 3094 Microbiota-neuroimmune interactions in a humanized mouse model of IBS: The role of diet and mast cells
Abstract
Gut immune system, microbiota and diet appear to play important roles in irritable bowel syndrome (IBS). Increased levels of colonic mast cell (MC) located in close proximity to mucosal nerves were reported in IBS patients, correlating with increased abdominal pain. We showed recently that IBS patients’ beneficial response to a low-fermentable diet was associated with changes in gut microbiota and urinary histamine. Here we investigated the …
Authors
Shimbori C; De Palma G; Reed D; Pigrau M; Lu J; Zhang Y; Yu Y; Jimenez-Vargas N; Sessenwein J; Lopez-Lopez C
Volume
76
Pagination
pp. e15-e16
Publisher
Elsevier
Publication Date
February 2019
DOI
10.1016/j.bbi.2018.11.220
Conference proceedings
Brain Behavior and Immunity
ISSN
0889-1591