Journal article
Application of Neuromelanin MR Imaging in Parkinson Disease
Abstract
MRI has been used to develop biomarkers for movement disorders such as Parkinson disease (PD) and other neurodegenerative disorders with parkinsonism such as progressive supranuclear palsy and multiple system atrophy. One of these imaging biomarkers is neuromelanin (NM), whose integrity can be assessed from its contrast and volume. NM is found mainly in certain brain stem structures, namely, the substantia nigra pars compacta (SNpc), the …
Authors
He N; Chen Y; LeWitt PA; Yan F; Haacke EM
Journal
Journal of Magnetic Resonance Imaging, Vol. 57, No. 2, pp. 337–352
Publisher
Wiley
Publication Date
February 2023
DOI
10.1002/jmri.28414
ISSN
1053-1807