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The CARM1 transcriptome and arginine...
Journal article

The CARM1 transcriptome and arginine methylproteome mediate skeletal muscle integrative biology

Abstract

OBJECTIVE: Coactivator-associated arginine methyltransferase 1 (CARM1) catalyzes the methylation of arginine residues on target proteins to regulate critical processes in health and disease. A mechanistic understanding of the role(s) of CARM1 in skeletal muscle biology is only gradually emerging. The purpose of this study was to elucidate the function of CARM1 in regulating the maintenance and plasticity of skeletal muscle. METHODS: We used …

Authors

vanLieshout TL; Stouth DW; Hartel NG; Vasam G; Ng SY; Webb EK; Rebalka IA; Mikhail AI; Graham NA; Menzies KJ

Journal

Molecular Metabolism, Vol. 64, ,

Publisher

Elsevier

Publication Date

October 2022

DOI

10.1016/j.molmet.2022.101555

ISSN

2212-8778